Published Studies

PANS and PANDAS Treatment Guidelines

In July 2017, the Journal of Child and Adolescent Psychopharmacology (JCAP) published a revised set of treatment guidelines for Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Disorder Associated with Streptococcal infection (PANDAS). The treatment recommendations, developed by a panel of leading clinicians and researchers, focus on three areas:

JCAP PANS / PANDAS Edition
Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I
Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part I - Psychiatric and Behavioral Interventions

PUBLISHED: Journal of Child and Adolescent Psychopharmacology

This article outlines the consensus guidelines for symptomatic treatment for children with Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS) and Pediatric Autoimmune Neuropsychiatric Syndrome Associated with Streptococcal infection (PANDAS).

Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part 2
Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part II - Use of Immunomodulatory Therapies

PUBLISHED: Journal of Child and Adolescent Psychopharmacology

Comprehensive treatment protocols must include immunological interventions, but their use should be reserved only for PANS cases in which the symptoms represent underlying neuroinflammation or postinfectious autoimmunity

Clinical Management of Pediatric Acute-Onset Neuropsychiatric Syndrome: Part III - Treatment and Prevention of Infections

PUBLISHED: Journal of Child and Adolescent Psychopharmacology

PANS and PANDAS, are emerging autoimmune encephalopathies of childhood. Management guidelines are needed. This article, from the PANS/PANDAS Consortium, presents a consensus management guideline for the infection components.

Learn how the Autoimmune Brain Panel™ can aid in the diagnosis of PANDAS & PANS.