Webinars
Neurologic, psychiatric and behavioral symptoms that don’t respond to typical treatments: How infections can trigger the immune system to disrupt the brain and the biomarker targets in the Autoimmune Brain Panel
Webinar Info
- Speaker: Craig Shimasaki, PhD, MBA – President & CEO, Moleculera Biosciences
- Aired: October 15, 2024
ABOUT THE WEBINAR
Brain on Fire: How infections and immune dysfunction can cause neuropsychiatric symptoms
Common infections (i.e., strep, influenza and mycoplasma pneumoniae) can trigger an abnormal autoimmune response, in which antibodies produced to destroy harmful pathogens (i.e., bacteria, viruses) mistakenly attack portions of the brain. This autoimmune attack disrupts how cells and receptors function and causes brain inflammation, resulting in a range of neuropsychiatric symptoms.
This presentation will review the biological process behind these infection-triggered autoimmune neuropsychiatric disorders. Dr. Shimasaki will discuss how infections can impact the immune system and the brain, leading to the onset of various neurologic and psychiatric symptoms, including OCD, tics, depression, anxiety and even seizure-like movements.
Dr. Shimasaki will describe several signs and symptoms that may help identify individuals with an autoimmune-induced neuropsychiatric condition. He will also review how testing with the Autoimmune Brain Panel™ can assist clinicians in determining whether symptoms may be due to an autoimmune response, rather than a primary neurologic or psychiatric disorder.
The presentation will highlight several patients who, after testing positive on the Panel, were treated successfully with a complete resolution of their symptoms.
PRESENTER
Craig Shimasaki is President and CEO of Moleculera Biosciences, a neuroimmunology precision medicine company focused on identifying underlying roots of neurologic, psychiatric, and behavioral disorders triggered by an autoimmune response. He is a medical research scientist with over 35 years of translational development experience in biochemical interactions, molecular biology, viral pathogenesis and infection-triggered neuropsychiatric disorders.
Dr. Shimasaki has worked at all stages of research and development from bench to bedside. His research included epitope mapping of HIV proteins, genetic based risk predictors of breast cancer, influenza and RSV diagnostics and therapeutics and pathogenesis of infection triggered neuropsychiatric disorders. As a businessperson, he co-founded multiple companies and led multiple products through the FDA approval process and is a co-inventor on multiple patents.
Dr. Shimasaki started his career at Genentech. He received his BS in Biochemistry from University of California at Davis, his PhD in Molecular Biology from the University of Tulsa, and his MBA from Northwestern University, Kellogg School of Business. He is an Adjunct Professor at the University of Oklahoma where he teaches biotechnology entrepreneurship. His passion is to help translate scientific and medical discoveries into acutely needed products so that more patients can live healthier lives.
Disclosure
The webinar content has been made available for informational purposes only. The information provided is not intended to be medical or healthcare advice for any individual medical problem, nor a substitute for medical or professional advice and services from a qualified healthcare provider.
By attending or viewing the webinar, you acknowledge and agree that we have not represented that any content provided in this webinar has the ability to diagnose a medical condition, prescribe treatment, or perform any other tasks that constitute the practice of medicine.
Moleculera hereby disclaims any and all liability to any party for any direct, indirect, implied, punitive, special, incidental, or other consequential damages arising directly or indirectly from any use of the webinar content, which is provided as is, and without warranties.
All rights reserved. No part of this presentation may be reproduced, distributed, or transmitted in any form or by any means, including recording, photocopying, or other electronic or other methods without the prior written consent of the publisher.
Scroll through the video to watch specific chapters. Click below.
4:25 – Financial impact on families
5:43 – Neuropsychiatric symptoms treated, not etiology or cause
8:58 – Study: Can infections cause neuropsychiatric symptoms?
10:14 – How does this occur biologically?
12:02 – Brain on Fire: Story of Susannah Cahalan
15:42 – Long-COVID and immune dysfunction
16:25 – Infections associated with these autoimmune encephalopathies
16:56 – How autoimmune response occurs
19:00 – Precision medicine to treat patients
19:34 – When infections trigger autoimmune response against the brain
20:28 – Symptoms correlate with biomarkers in Autoimmune Brain Panel
22:58 – Case study: 8-year-old female
24:53 – Case study: 16-year-old female
26:38 – Case study: 20-year-old female
28:21 – Case study: misdiagnosed with schizophrenia
29:36 – Patient success stories
30:36 – Diagnosis and treatment guidelines
31:25 – Commonalities among patients tested with the Autoimmune Brain Panel